| PAS_1 |
This plant has been used traditionally for medicinal purposes. The plant possesses anti-inflammatory, antimetastatic, antitumor, coagulant and anti-coagulant (dose dependent), disinfectant, antiparasitic, wound healing, insecticidal, pregnancy terminating activity and antidiarrhoeal effect. The main constituents of the plant are curcin, curcusone-B, curcain etc. Apart from this, the plant also contains toxic principle such as tetramethylpyrazine (TMPZ). [Laxane, Sumit & Swarnkar, Surendra & Kenganora, Mruthunjaya & Zanwar, S.B. & Manganahalli, Manjunath. (2013). Jatropha curcas: A systemic review on pharmacological, phytochemical, toxicological profiles and commercial applications. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 4. 989-1010.] https://www.researchgate.net/publication/287271508_Jatropha_curcas_A_systemic_review_on_pharmacological_phytochemical_toxicological_profiles_and_commercial_applications#:~:text=This%20plant%20has%20been%20used,terminating%20activity%20and%20antidiarrhoeal%20effect. |
| PAS_2 |
Methanolic and hot water extracts of kernel meal showed antimicrobial activity against both Gram positive and Gram negative pathogenic bacteria (inhibition range: 0–1.63 cm) at the concentrations of 1 and 1.5 mg/disc. Methanolic extract exhibited antioxidant activities that are higher than hot water extract and comparable to β-carotene. The extracts tended to scavenge the free radicals in the reduction of ferric ion (Fe3+) to ferrous ion (Fe2+). Cytotoxicity assay results indicated the potential of methanolic extract as a source of anticancer therapeutic agents toward breast cancer cells. [Oskoueian E, Abdullah N, Ahmad S, Saad WZ, Omar AR, Ho YW. Bioactive compounds and biological activities of Jatropha curcas L. kernel meal extract. Int J Mol Sci. 2011;12(9):5955-5970. doi:10.3390/ijms12095955] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189762/ |
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